Microneedles (MNs) are promising tools for drug delivery since they
offer transdermal delivery without pain, bleeding and skin deformation thanks to their small sizes
suppress needle phobia and anxiety in patients
provide practical use and so self-administration by the patient
eliminate accidental needle stuck injuries
enable significant dose sparing
Carbon Nanotubes in Microneedle Fabrication
MNs of various functionalities have been fabricated by many researchers using various materials and fabrication techniques. The applicability and success of the MN mediated drug delivery largely depend on the simplicity of the fabrication and functionalities of MNs. In this respect, carbon nanotube (CNT) looks an ideal material in MN fabrication when the simplicity and flexibility of its synthesis are considered. The entire geometry of hollow MNs can be fabricated by catalyst patterning and vertical growth of CNTs via chemical vapor deposition (CVD). So, an array of patterned CNT bundles, fabricated by CVD, can be used as a scaffold for MNs.
What We Aim?
Perhaps the biggest problem that hollow MNs face with is their low flow rate drug deliveries. From drug delivery tests, it has been reported many times that the flow rate is significantly slowed down by the skin compression to the tip of hollow MNs. This causes long waiting time for patients and consequently reduces the applicability of the method. Our goal in this research is to fabricate high flow rate CNT MNs by designing a novel needle head which prevents the skin compression.